AP Biology Wet and Virtual Labs


Big Idea 1: Evolution

Evolution drives the diversity and unity of life. Supported by evidence from many scientific disciplines, Darwin’s theory of evolution states that heritable variations occur in individuals in a population; because of competition for resources, individuals with more favorable phenotypes are more likely to survive and reproduce, thus passing traits to offspring.

Investigation 1:
Artificial Selection

Evolution Lab - simulation showing how organisms evolve over time in response to environmental conditions

Natural Selection at PHET - another simulation showing wolf and rabbit populations

Sex and the Single Guppy - simulation that examines sexual selection

Case Study: "I'm Looking Over a White-Striped Clover" - an investigation of clover adaptations

Evolution of the Origami Bird - this uses a paper model that flies, coin flips represent variations in wing position and length


Investigaton 2:
Mathematical Modeling: Hardy Weinberg

Hardy Weinberg Presentation &
Hardy Weinberg Problem Set

Count individuals and use the HW equation to determine allele frequencies

Hardy Weinberg Simulation - uses beads to represent alleles, track changes in generations using students as "parents"


Investigation 3:
Comparing DNA Sequences to Understand Evolutionary Relationships with BLAST

Bacterial ID Lab at HHMI - this includes a BLAST section and a simulation of isolated and identifying bacteria using PCR amplification

Name That Gene - using blast, identify genes using DNA sequences

Constructing a Cladogram - drawings are used to infer relationships and create a cladogram

Cladogram Analysis -image of a cladogram of arthropods where students determine derived characteristics and create their own cladogram

Examining the Fossil Record - fossils are arranged on a poster to show how each are related and how speciation can occur


Big Idea 2: Cellular Processes

Biological systems utilize free energy and molecular building blocks to grow, reproduce, and maintain dynamic homeostasis.

Organisms have evolved various strategies to capture, use, and store free energy and other vital resources.


Investigation 4: Diffusion and Osmosis

Flinn Science Wet Lab


Investigation 5: Photosynthesis

Photosynthesis Simulation - change light intensity and wavelength and compare the amount of ATP produced

Waterweed Simulator - Adjust light and CO2 levels, measure photosynthesis by counting bubbles


Investigation 6: Cellular Respiration

Virtual Lab: Cellular Respiration - a step-through activity that mirrors the procedure of the investigation


Big Idea 3: Genetics and Information Transfer

Genetic information provides for continuity of life, and, in most cases, this information is passed from parent to offspring via DNA. In Eukaryotic organisms, heritable information is packed into chromosomes that are passed to daughter cells by mitosis, a controlled mechanism that ensures that each daughter cell receives an identical and complete complement of chromosomes.

Investigation 7: 
Cell Division: Mitosis and Meiosis

Mitosis Internet Lesson-
Meiosis Internet Lesson - use various sites to observe models of mitosis and meiosis

Linkage Group Simulation - pipe cleaners are used to model crossing over


Investigation 8:
Biotechnology: Bacterial Transformation

Transgenic Fly Virtual Lab - HHMI uses a virtual lab to insert DNA into flies which are used to study circadian rhythms

Recombinant DNA Simulation - using paper to model how restriction enzymes can be used to modify DNA


Investigation 9:
Biotechnology: Restriction Enzyme Analysis of DNA

Wet Lab:  DNA Extraction - extract DNA from a strawberry


Big Idea 4: Interactions

Living systems from cells to ecosystems require free energy and matter to maintain order, grow, and reproduce, with organisms using various strategies to capture, use, and store free energy and other resources.

Investigation 10:
Energy Dynamics

Virtual Lab: Population Biology - observe the competitive exclusion principle in populations of paramecium

Case Study - The Gulf's Dead Zone - presentation case that presents information and asks students to evaluate, analyze and make recommendations


Investigation 11:

McGraw-Hill Biology Virtual Lab Exercises.



Investigation 12:
Fruit Fly Behavior

McGraw-Hill Biology Virtual Lab Exercises.



Investigation 13:
Enzyme Activity

McGraw-Hill Biology Virtual Lab Exercises